Since it affects women more, gender is definitely an important risk factor for SCAD.

Fibromuscular dysplasia, an irregular growth of cells in the artery walls, is another big risk factor that leads to SCAD. It has been found that women are more likely to develop Fibromuscular dysplasia than men which makes them more prone to developing SCAD.

Genetic reasons like diseases associated with connective tissue, vascular Ehlers-Danlos syndrome and Marfan syndrome are also associated with SCAD.

Extremely high blood pressure is also associated with SCAD.

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